The combination of sulfamethoxazole and trimethoprim is a great example of synergistic action. What enzyme does...
The combination of sulfamethoxazole and trimethoprim is a great example of synergistic action. What enzyme does trimethoprim inhibit to enhance the inhibition of folic acid synthesis? explain
Homework Answers
Ans.
Trimethoprim inhibits DIHYDROFOLATE REDUCTASE which change dihydro follic acid to tetrahydro folic acid.
Tetrahydro folic acid is essential for nucleotide synthesis in bacterial cell.
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