Question

Which of the following are key discoveries of the experiments conducted by Brown and Goldstein?

1) Cholesterol is taken into cells through the action of a specific receptor.
2) The receptor for the LDL particle recognizes B-100 apolipoprotein.
3) The entire receptor complex, unlike hormones involved in signaling pathways, enters the cell via endocytosis.
4) Familial hypercholesterolemia patients have defective or deficient LDL receptors.

Statements 1, 2, and 4 are correct. O Only statements 1 and 4 are correct. Statements 1, 2, and 3 are correct. o All of the listed statements are true

Answer 1

The correct statement is : All of the listed statements are true.

Reason:Brown and Goldstein experiments concluded all of the above mentioned statements are true when they carried out experiments to study cholesterol metabolism in human cells.