Draw the following peptide at physiological pH.
Gln-ser-his

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utility.
Draw the following peptide at physiological
pH.
Gln-ser-his
Н н Н Н H3N C N- C -N- C co O C I IZ
1) Draw the polypeptide: Ser-Gln-His-Ser II) Estimate the net charge of the polypeptide that has the sequence of Glu-His-Trp-Ser-Gly-Leu-Arg-Pro-Gly 1) At pH 7 2) At PH 11 Pka values are given in table 3.2
Predict the charge on the major species of the peptide Ile–Arg–Asp–Ala–Lys–Ser–Gln at pH 7.0
5. Consider the following peptide: His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gin- Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr a. What are the fragments, if it is cleaved by trypsin? b. What are the fragments, if it is cleaved by chymotrypsin? c. What are the fragments, if it is cleaved by pepsin?
Predict the charge on the major species of the peptide Ile-Lys-Asp-Arg-Ser-Gln at pH 7.0 Please explain if you can. Thanks
Draw the structure of the peptide GlnCysAlaMet at pH = 7.0 (Gln pka(NH3)= 9.13, Cys (SH)=8.3, Met (C terminal)=2.13)
19. Calculate the net charge on the following nonapeptide at the physiological pH 7.4, and predict the peptide's mobility in an electric field. Explain your answer. (4 pts) Gln-Tyr-Ala-Phe-Gly-Cys-Ser-His-Asp.
Draw structure of this peptide at pH 7 and at pH 11. Ala-Arg-Asn-Asl-Glu-Ser-Gly Asp*
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Draw the following peptide at physiological pH. Lys-trp-pro
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Н н Н Н H3N C N- C -N- C co O C I IZ
a) Draw the structure of a Gln-Lys-Met tripeptide at pH 7. b) Calculate the pl of the peptide. Show your work.