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What would be the consequence of a dysfunctional Glutamine Synthetase enzyme? How will nitrogen levels from...

What would be the consequence of a dysfunctional Glutamine Synthetase enzyme? How will nitrogen levels from this dysfunctional enzyme effect the body?

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The enzyme glutamine synthetase have a significant role in controlling of nitrogen metabolism/ assimilation and leads to the production of glutamin. The dysfunctional Glutamine synthetase enzyme can lead to ineffective nitrogen metabolism control and will create urgent need of glutamine (as its responsible for the syntessis of various essential amino acids) because ammonia is assimilated to form glutamine, finally it will cause imbalance in the nitrogen level.

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