Question

Please design a drug that is an antimicrobial (antibacterial, antifungal, antiviral, and antihelminth), yes a magic bullet. You must explain the mode of action of the antibacterial, antiviral, antifungal and antihelminth portions of your magic bullet. Please explain how your drug will be administered to your patient, and how would you test your drug? Make sure you choose your target sites on each microbe very carefully so you achieve selective toxicity and limiting side effects in your patient

Answer 1

Answer:

Answer: there are various mode of Action followed by Antimicrobial Aquits to block or minimize impact dl the patho quic behaviour. those Mechanisms are listed below Inhibition Well wall & membrane:- A drug which is Specific for bacterial cell wall, that will bind with wall syn the sizing bacteria So it will make them emable to grow . there are various examples of such Antimicrobial Agents ice. Vomomiya, bacitracin oud Cephalospovins etc. Jews of Species Regulate the Movement o material through Cell Mumbrome, which got effected becouse Antimicrobial Aquits such as colistin, Polymixin.B.

Inhibition o protein Synthesis:- Some Antiani vobiad Aquits target the specific protuis which are essential for Microorganism such as 30s and los Ribosomal unit Blocking oud destruction of these proteins will leads to disruption d Cellular process. For exemple Amino glycosides, tetracyclimes ond step to queuins Drug Combe treated using the rapid diagnostic kit, where the structre comptability with the pathoque con be tested - Suppose we have designed the drug has the compatibility with Antique protein- using the Wi con visualize the interaction between the protuns of outiqen and Antibactivial As the most o discose target sites are known . In that lose we can design the Antique coated CELisa plate EList Hechnique

After that incubation of magic bullet' togquol with Substrate Second step will be washing of tlist will and Add the enzyme linked Antibody. If there will be unteraction between Antique and Anntinnicrobial drug then color change will be observed. Second method is to test your olrug is through the Animal model where the drug will Adanimi strated in Animal model Alter that the Activity of drug com Moosaved According to the navomieter of Antique degradation when there was a cose of Administrated drug we loont to lind it Activeness in host simplev Method is to observe the Chouge in behaviour of patient

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