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Question 19 In a serine protease, the oxyanion hole binds to ATP stabilizes the tetrahedral intermediate. is the reactive gro
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ANS-19) In a serine protease, the oxyanion hole (b) stabilizes the tetrahedral intermittent.

The catalytic role of the oxyanion hole in serine protease is generally established to be in stabilizing high-energy intermediates and the transition state through hydrogen bonding.

ANS-20) What molecule tags proteins for destruction by the proteasome? (c) Ubiquitin.

Proteasomes are part of a major mechanism by which cells regulate the concentration of particular proteins and degrade misfolded proteins. Proteins are tagged for degradation with a small protein called ubiquitin.

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