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Question 25 What process results in a total loss of protein function? O denaturating hydrogen bonding hydrolysis esterificati
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Denaturating is the process which results in a total loss of protein function.

Protein found in a biological system with a unique three-dimensional structure and biological activity is called a native protein. When a protein in its native form, is subjected to physical change like change in temperature or chemical change like change in pH, the hydrogen bonds are disturbed. Due to this, globules unfold and helix get uncoiled and protein loses its biological activity. This is called denaturation of protein. During denaturation 2° and 3° structures are destroyed but 1º structure remains intact. The coagulation of egg white on boiling is a common example of denaturation.

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