Which of the following adaptor proteins activate the NF- B pathway? A. MyD88 B. IKK-alpha C....
Which of the following adaptor proteins activate the NF- B pathway?
A. MyD88
B. IKK-alpha
C. Calmodulin
D. IL-2 receptor
E. IRF
Homework Answers
Answer. B. IKK-alpha.
When the IKKb is activated, it is shown to play a role in the phosphorylation of IkB. The IkB, upon phosphorylated, gets ubiquitinated and this becomes a marking for its degradation by proteases. This, then further releases NF-κB from the IkB-containing complex. Once the NF-κB gets released, the nuclear localization signal gets unmasked.
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Which of the following adaptor proteins activate the NF- B
pathway?
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B. IKK-alpha
C....
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Last guy got it wrong - Thank you. 2. You discover a signal transduction pathway that...
Last guy got it wrong - Thank you.
2. You discover a signal transduction pathway that regulates actin polymerization. SigC is the ligand, which binds to and activates a receptor tyrosine kinase (RTK). Activation of the RTK leads to the activation of the Ras protein, which then activates the protein kinase PK1 that phosphorylates the RingA protein on S34. When SigC plasma membrane phosphorylated, RingA binds EXTRACELLULAR to the gene regulatory SPACE inactive Ras protein activated Ras protein protein, AP1....
NF-kappa B (NFKB) proteins are transcription factors that control the expression of genes involved in cellular processes such as proliferation, differentiation inflammation, and apoptosis. Dysfunction within the NFkB pathway can trigger indefinite cell proliferation and cell survival leading to the development of tumors. Stimul OS NIYA W IDTNOM IMAM IMENOVE 1. Explain how NFKB proteins are activated to promote cell survival. 2. How would a cell evade apoptosis if an IB Inhibitor of kappa B) protein could no longer bind...
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QUESTION Which of the following is not a role of proteins in a signaling pathway? They phosphorylate GDP TO GTP. They act as switches to turn acties on and off They interact with GTP They interact with receptors and stimulate cellular activities
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Last guy got it wrong - Thank you.
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