Question

Within a prokaryotic cell, bacteria, you will find peptidoglycan. This is a component only found in bacteria. The role of this compound, peptidoglycan, is to give bacteria its rigid structure within the cell wall. This is what protects certain substances from entering the bacteria, this sturdy wall provides support and strength to the bacteria. Peptidoglycan is composed of, to simplify, sugar and proteins that allow the cell wall of bacteria to be strong and bendy. Another reasons why peptidoglycan is important is because it is what also allows bacteria to multiply.  

Please share whether or not you think the structure mentioned in the above paragraph would be a good target for antibiotics and why? ‌

Answer 1

ANSWER :-

1. The peptidoglycan is a molecule which is made up of two components namely the amino acids (in the form of peptides) and glucose residues. These two components plays an important role being an integral part of the cell wall and helps in providing protection to the cell.
2. Inside the cell wall, it should be noted that the concentration of solute is more as compared to that of the surroundings and this is turn according to the laws of osmosis will lead to the swelling of the cell and eventually damaging the cell.
3. In case of certain type of bacteria such as the Gram positive bacteria, there is presence of peptidoglycan layer. So, antibiotics if are directed towards the peptidoglycan layer would be involved in mediating cell damage as certain antibiotics discovered are being targetted to alter the synthesis of this peptidoglycan layer. This can mediate cell damage.