Q1:Rank the following leaving groups from best (top) to worst (bottom) in nucleophilic substitution reaction: Br, I, F, Cl.
Q2:
The silica gel TLC below shows analysis of fractions collected after column chromatography of the crude reaction mixture obtained in Williamson Ether Synthesis lab ("mixture" is the spot of the reaction mixture before column). Which fractions (1-6) should be collected to obtain pure product? Enter the corresponding fraction numbers separated by comma (i.e., 1,2,etc.)

Word Answer:
Q1:Rank the following leaving groups from best (top) to worst (bottom) in nucleophilic substitution reaction: Br,...
Determine the yield limiting reagent and the theoretical yield for the following multistep synthesis from the reaction of ethyl acetoacetate. Draw the chemical complete chemical reaction and mechanism of Product C (determined to be 4-hydroxy-4 4-diphenylbutan-2-one) to Product E provided the procedure below. Procedure Step 4B [Product C to Product E] Place product [C] (0.5 g) in a 50 mL round bottomed flask, add acetone (15 mL), and concentrated HCl (2.5 mL). Boil under reflux on a water bath for...
need work and answers
IlI. Preparation of Synthetic Eugenol (10 pts) Eugenol, the main component of clove oil, can be prepared from heating 2-allyl guaiacol (in the absence of oxygen) to temperatures>205 °C. In practice, however, it is most cost effective to extract eugenol from cloves, its natural source. Given a weight percentage of eugenol in cloves at-15%, calculate the minimum mass of cloves one needs to obtain 1.00 g of eugenol as product? Report your answer below. Show your...
If you were to run this reaction on a 0.5 g acetaminophen, how
much powdered potassium carbonate would you use ? Show your
work
Alcohols and Ethers 185 14.3 THE WILLIAMSON ETHER SYNTHESIS: PREPARATION OF PHENACETIN FROM ACETAMINOPHEN One of the most common methods used to prepare ether Williamson ether synthesis. In this reaction, an alkoxide anion (RO) acts as a nucleophile in an S, 2 process, displacing a leaving group (X) from an electrophile (R-X). R-20 . RY ROR...
need work and answers
IlI. Preparation of Synthetic Eugenol (10 pts) Eugenol, the main component of clove oil, can be prepared from heating 2-allyl guaiacol (in the absence of oxygen) to temperatures>205 °C. In practice, however, it is most cost effective to extract eugenol from cloves, its natural source. Given a weight percentage of eugenol in cloves at-15%, calculate the minimum mass of cloves one needs to obtain 1.00 g of eugenol as product? Report your answer below. Show your...
Need help, numbers 3-6 please show work. and fill out table of
chemicals for all chemical used.
calculate mmol in the table as well show work please
and each of these must be listed in its own row. There are 10 column headings: IUPAC name OR common name, structure, CAS number (Chemical Abstract Service number) molecular mass, melting point (if applicable), boiling point (if applicable), solubility (in water, if applicable), density, amounts to be used in the experiment, and the...
Evaluate and investigate the
following IR Spectrum, 13C NMR Spectrum
and 1H NMR Spectrum. Identify
the most important peaks and correlate the
results as much as you can from the obtained product in
the multi-step synthesis of ethyl acetoacetate.
This is Product E from this multi-step synthesis
where Product C was identified as in the figure
below and as such, identify what product can be obtained
after the synthesis from the spectra provided. Use the template
below in analysing the...