Which of the following execise (S) allosteric control in the reaction of the phosphofructokinase A) ATP...
Which of the following execise (S) allosteric control in the reaction of the phosphofructokinase
A) ATP
B)fructose 2,6 biphosphate
C) both of these
D) none of these
Homework Answers
C) both ATP & fructose 2,6 bisphosphate. The enzyme phosphofructokinase is important enzyme of glycolysis pathway. The enzyme phosphofructokinase carried out conversion of fructose 6 phosphate and ATP into fructose 1,6 bisphosphate and ADP. The important allosteric activators of phosphofructokinase is fructose 2,6 bisphosphate.
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Which of the following execise (S) allosteric control in the
reaction of the phosphofructokinase
A) ATP...
Training Question 3. Shown below is the activity profile for the enzyme phosphofructokinase-1 (PFK-1) which catalyzes...
Training Question 3. Shown below is the activity profile for the enzyme phosphofructokinase-1 (PFK-1) which catalyzes the reaction: Fructose 6-phosphate + ATP → fructose 1,6-biphosphate + ADP. Low (ATPI PFK-1 activity High (ATP) [Fructose 6-phosphatel Describe the different patterns of regulation for different ATP levels. Explain the why such regulation is appropriate for this enzyme, given its role in metabolism.
In an ATP synthase which has 12 copies of the c subunit, how many protons move...
In an ATP synthase which has 12 copies of the c subunit, how many protons move through the enzyme for each one ATP that is synthesized? 44. 4 12. 45. An uncoupler acts by: a. Inhibiting a redox couple b. nhibiting proton pumping complexes. c. nhting oxygen reduction d. Collapsing the proton gradient e. Uncoupling the F and Fo subunits of the ATP synthase GLUCONEOGENESIS The reactions of glycolysis that are replaced by different enzymes in the gluconeogenesis pathway are...
Les one phonphate A) (3 pts) What is the role of fructose 6-phosphate in the PFK...
Les one phonphate A) (3 pts) What is the role of fructose 6-phosphate in the PFK catalyzed reaction as seen in graph Arch (A) Substrate; (B) Allosteric inhibitor; (C) Allosteric activator; (D) None of the above B) (3 pts) What is the role of fructose 2.6-bisphosphate (F-2,6-BP) in the PFK catalyzed reaction as seen Choose between: (A) Substrate; (B) Allosteric inhibitor; (C) Allosteric activator; (D) None of the above C) (4 pts) What are the 2 roles of ATP in...
Why is the activity of Phosphofructokinase (PFK-1) high at moderate concentrations of ATP and low at...
Why is the activity of Phosphofructokinase (PFK-1) high at moderate concentrations of ATP and low at high concentrations of ATP? When there is a lot of ATP, it gets consumed more rapidly in other processes, which decreases the ability of PFK-1 to use it. ATP is a competitive inhibitor of PFK-1. At high concentrations ATP is an allosteric inhibitor of PFK-1. ATP phosphorylates PFK-1, inactivating it. What is required for fermentation? O2 ATP NADH Pyruvate Both NADH and pyruvate
Which of the following statements about allosteric control of enzymatic activity is false. A. Allosteric enzymes...
Which of the following statements about allosteric control of enzymatic activity is false. A. Allosteric enzymes show strict Michaelis-Menten Kinetics B. Allosteric modulators give rise to sigmoidal V) vs. [S] kinetic plots C. A modular may either inhibit or activate an enzyme D. Binding of the modular changes the conformation of the enzyme molecule
PART A OPTIONS FOR BLANKS: 1- inhibits, does not affect, stimulates 2- fructose-1,6-biphosphatase-1, pyruvate kinase, phosphofructokinase-1...
PART A OPTIONS FOR BLANKS:
1- inhibits, does not affect, stimulates
2- fructose-1,6-biphosphatase-1, pyruvate kinase,
phosphofructokinase-1
3- phosphofructokinase-1, fructose-1,6-biphosphatase-1,
phosphoenolpyruvate carboxylate
PART B OPTIONS FOR BLANK:
Activity Curve A, Neither, Activity Curve B
Part 1 (3 points) See Hint High levels of fructose-2,6-BP reciprocally regulate glycolysis and gluconeogenesis. Fructose-2,6-BP flux through the glycolytic pathway by increasing the activity of Flux through the gluconeogenic pathway is inhibited by fructose-2,6- BP, which decreases the activity of Part 2 (1 point) See Hint...
29. The activity of the enzyme phosphofructokinase is a) stimulated by low energy charge b) inhibited...
29. The activity of the enzyme phosphofructokinase is a) stimulated by low energy charge b) inhibited by fructose 2,6-bisphosphate c stimulated by fructose 1.6-bisphosphate d) all of the above 30. NADH is produced at a) aldolase catalyzed reaction b) Glyceraldehyde-3-phosphate dehydrogenase catalyzed reaction c) pyruvate kinase catalyzed reaction d) hexokinase catalyzed reaction 31. The transfer of 3-phosphoglycerate to 2-phosphoglycerate is catalyzed by which enzyme? a) PGM b)PK c)G2PDH d)TPI e)PFK 32. The enzyme aldolase catalyzes which reaction in Glycolysis? a)...
Question 4 Q . OH ATP OH POH ОН Fructose 6-phosphate Fructose 1.6-bisphosphate Figure 1. Reaction...
Question 4 Q . OH ATP OH POH ОН Fructose 6-phosphate Fructose 1.6-bisphosphate Figure 1. Reaction catalyzed by phosphofructokinase (PFK) during glycolysis Phosphofructokinase (PFK) is an enzyme that catalyzes the conversion of fructose 6- phosphate to fructose 1,6-bisphosphate during glycolysis, as represented in Figure 1. PFK can be allosterically inhibited by ATP at high concentrations. Which of the following is the benefit of regulating glycolysis by the concentration of ATP? Glycolysis proceeds when the intracellular concentration of ATP is low,...
Need help with this. I need to match the text box with the following hexokinase,aldolase,phosphofructokinase,enolase,aconitase,furmarase. Thanks...
Need help with this. I need to match the text box with the
following
hexokinase,aldolase,phosphofructokinase,enolase,aconitase,furmarase.
Thanks
10 pts Question 22 These enzymes are involved in Glycolysis and the Citric Acid cycle. Match the term with the correct function. Only one function is listed for each enzyme. Hexokinase [Choose Choose l Converts Citrate to isocitrate in 2 steps Succinate Dehydrogenase Aldolase Makes 2 three carbon molecules from Fructose 1.6 biphosphate Phosphorylates Fructose 6-phosphate in the presence of ATP Form Glucose 6....
MATCH THE FOLLOWING a. PFK-1 b. FBpase-1 c. PFK-2 d. FBpase-2 e.cAMP- dependent protein kinase (PKA)...
MATCH THE FOLLOWING a. PFK-1 b. FBpase-1 c. PFK-2 d. FBpase-2 e.cAMP- dependent protein kinase (PKA) WITH 1. makes F-2,6 -BP(fructose-2,6-biphosphate) 2. Activated by F-2,6-BP(fructose-2,6-biphosphate) 3. Activates the enzyme that breaks down F-2,6-BP 4. Inhibited by F-2,6-BP 5. Breaks down F-2,6-BP
Training Question 3. Shown below is the activity profile for the enzyme phosphofructokinase-1 (PFK-1) which catalyzes the reaction: Fructose 6-phosphate + ATP → fructose 1,6-biphosphate + ADP. Low (ATPI PFK-1 activity High (ATP) [Fructose 6-phosphatel Describe the different patterns of regulation for different ATP levels. Explain the why such regulation is appropriate for this enzyme, given its role in metabolism.
In an ATP synthase which has 12 copies of the c subunit, how many protons move through the enzyme for each one ATP that is synthesized? 44. 4 12. 45. An uncoupler acts by: a. Inhibiting a redox couple b. nhibiting proton pumping complexes. c. nhting oxygen reduction d. Collapsing the proton gradient e. Uncoupling the F and Fo subunits of the ATP synthase GLUCONEOGENESIS The reactions of glycolysis that are replaced by different enzymes in the gluconeogenesis pathway are...
Les one phonphate A) (3 pts) What is the role of fructose 6-phosphate in the PFK catalyzed reaction as seen in graph Arch (A) Substrate; (B) Allosteric inhibitor; (C) Allosteric activator; (D) None of the above B) (3 pts) What is the role of fructose 2.6-bisphosphate (F-2,6-BP) in the PFK catalyzed reaction as seen Choose between: (A) Substrate; (B) Allosteric inhibitor; (C) Allosteric activator; (D) None of the above C) (4 pts) What are the 2 roles of ATP in...
PART A OPTIONS FOR BLANKS:
1- inhibits, does not affect, stimulates
2- fructose-1,6-biphosphatase-1, pyruvate kinase,
phosphofructokinase-1
3- phosphofructokinase-1, fructose-1,6-biphosphatase-1,
phosphoenolpyruvate carboxylate
PART B OPTIONS FOR BLANK:
Activity Curve A, Neither, Activity Curve B
Part 1 (3 points) See Hint High levels of fructose-2,6-BP reciprocally regulate glycolysis and gluconeogenesis. Fructose-2,6-BP flux through the glycolytic pathway by increasing the activity of Flux through the gluconeogenic pathway is inhibited by fructose-2,6- BP, which decreases the activity of Part 2 (1 point) See Hint...
29. The activity of the enzyme phosphofructokinase is a) stimulated by low energy charge b) inhibited by fructose 2,6-bisphosphate c stimulated by fructose 1.6-bisphosphate d) all of the above 30. NADH is produced at a) aldolase catalyzed reaction b) Glyceraldehyde-3-phosphate dehydrogenase catalyzed reaction c) pyruvate kinase catalyzed reaction d) hexokinase catalyzed reaction 31. The transfer of 3-phosphoglycerate to 2-phosphoglycerate is catalyzed by which enzyme? a) PGM b)PK c)G2PDH d)TPI e)PFK 32. The enzyme aldolase catalyzes which reaction in Glycolysis? a)...
Question 4 Q . OH ATP OH POH ОН Fructose 6-phosphate Fructose 1.6-bisphosphate Figure 1. Reaction catalyzed by phosphofructokinase (PFK) during glycolysis Phosphofructokinase (PFK) is an enzyme that catalyzes the conversion of fructose 6- phosphate to fructose 1,6-bisphosphate during glycolysis, as represented in Figure 1. PFK can be allosterically inhibited by ATP at high concentrations. Which of the following is the benefit of regulating glycolysis by the concentration of ATP? Glycolysis proceeds when the intracellular concentration of ATP is low,...
Need help with this. I need to match the text box with the
following
hexokinase,aldolase,phosphofructokinase,enolase,aconitase,furmarase.
Thanks
10 pts Question 22 These enzymes are involved in Glycolysis and the Citric Acid cycle. Match the term with the correct function. Only one function is listed for each enzyme. Hexokinase [Choose Choose l Converts Citrate to isocitrate in 2 steps Succinate Dehydrogenase Aldolase Makes 2 three carbon molecules from Fructose 1.6 biphosphate Phosphorylates Fructose 6-phosphate in the presence of ATP Form Glucose 6....
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