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Formation of a replication fork results in: A. continuous synthesis of DNA on the lagging strand....

Formation of a replication fork results in:

  • A. continuous synthesis of DNA on the lagging strand.
  • B. supercoiling in the parental DNA ahead of the fork.
  • C. of new 3' -OH regions on the template DNA.
  • D. binding of SSB protein on the double-stranded parental DNA.
  • E. All of the above occur when the replication fork is formed.
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Answer #1

B. Supercoiling in the parental DNA ahead of the fork.

Formation of replication fork produces supercoiling ahead of the fork that increases the strain on parental DNA.

Continuous synthesis of new DNA occur on leading strand template.

3'OH is form by the introduction of RNA primer by NRA primase as DNA polymerase can not initiate polymerisation without 3'OH.

SSB protein binds on the separated single strands of DNA to to hold it separated from other strand.

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