What do we mean when we said that receptor-ligand interactions are reversible? Why is this important?
What do we mean when we said that receptor-ligand interactions are reversible? Why is this important?
Homework Answers
ANSWER:
By reversible receptor ligand interaction we mean that the binding or attachment of the ligand on the receptor can be reverted once the process of activation or inactivation to be caused by the receptor ligand interaction is completed and the binding between the receptor and ligand is non- covalent binding and thus the receptor can be reused to carry another set of reactions.
This non covalent interaction is of great significance as the same ligand is available to interact with multiple receptor subtypes. Thus a small concentration of ligand can work for longer time period and can be reused by the receptors to have an effect.
Add Answer to:
What do we mean when we said that receptor-ligand interactions
are reversible? Why is this important?
The binding of a ligand to a receptor is important for allowing external signals to affect...
The binding of a ligand to a receptor is important for allowing external signals to affect intracellular processes. Which property of receptor proteins is key for this signaling to occur? Select one: a. Non-reversible binding to ligand b. Non-rigid structure that allows for conformational changes when a ligand binds c. Non-specific interactions with extracellular molecules d. Non-specific interactions with intracellular molecules
D5. Receptor-ligand interactions and enzyme-substrate interactions are similar because they both involve highly specific binding both...
D5. Receptor-ligand interactions and enzyme-substrate interactions are similar because they both involve highly specific binding both the ligand and the substrate undergo a chemical change both the receptor and the enzyme alter their activities after the interaction they both rely on covalent binding D 6. Electron carriers like NADH and FADH2 are what type of molecules? enzymes receptors lipids proteins coenzymes
Give one example of a ligand-receptor pair for each of the six generic types of cell...
Give one example of a ligand-receptor pair for each of the six generic types of cell signaling. Do not include the details of the pathway, just give its name and how/why it is important to the cell. Line up the six generic types, using the generix names, according to soeed of the signaling process and give an explanation of the order that you determined. I'm guessing the six types are: GCPR Receptor Tyrosine Kinase Receptor Guanylyl Cyclase Adhesion receptor (integrin)...
What does it mean if a beta blocker is classified as cardioselective? It's selective for what receptor? What is the...
What does it mean if a beta blocker is classified as cardioselective? It's selective for what receptor? What is the overall effect of adreneric drugs on the heart and cardiovascular system? What is the overall effect of adrenergic drugs on the eye? What is the overall effect of adrenergic drugs on bronchial smooth muscle? What is the overall effect of adrenergic drugs on the urinary bladder? What is an important potential toxicity of atropine and other muscarinic antagonists in infants...
Why do we claim that leading by example is extremely important? What are some of the...
Why do we claim that leading by example is extremely important? What are some of the problems that can arise when we fail to do so?
Acetylcholine is the substrate for the enzyme acetylcholinesterase. 1. Suggest what sort of binding interactions could...
Acetylcholine is the substrate for the enzyme
acetylcholinesterase.
1. Suggest what sort of binding interactions could be involved
in holding acetylcholine to the active site.
2. The ester bond of acetylcholine is hydrolysed by
acetylcholinesterase. Suggest a mechanism by which the enzyme
catalyses this reaction.
3. Suggest how binding interactions might make acetylcholine
more susceptible to hydrolysis.
4. Structure I is an agonist which binds to the cholinergic
receptor and mimics the action of the natural ligand acetylcholine.
Structure II,...
When defining a system, what do we mean by structure, and what do we mean by...
When defining a system, what do we mean by structure, and what do we mean by function? Then explain a system, and describe it in terms of its structure and function.
What is "socialization?" Why is it important? How do we become "socialized?
What is "socialization?" Why is it important? How do we become "socialized?
What is it important to do when warming insulin before use? Why is this important?
What is it important to do when warming insulin before use? Why is this important?
What does it mean to tare a balance and why do you think it is important...
What does it mean to tare a balance and why do you think it is important to complete this before you begin measuring mass?
D5. Receptor-ligand interactions and enzyme-substrate interactions are similar because they both involve highly specific binding both the ligand and the substrate undergo a chemical change both the receptor and the enzyme alter their activities after the interaction they both rely on covalent binding D 6. Electron carriers like NADH and FADH2 are what type of molecules? enzymes receptors lipids proteins coenzymes
What does it mean if a beta blocker is classified as cardioselective? It's selective for what receptor? What is the overall effect of adreneric drugs on the heart and cardiovascular system? What is the overall effect of adrenergic drugs on the eye? What is the overall effect of adrenergic drugs on bronchial smooth muscle? What is the overall effect of adrenergic drugs on the urinary bladder? What is an important potential toxicity of atropine and other muscarinic antagonists in infants...
Acetylcholine is the substrate for the enzyme
acetylcholinesterase.
1. Suggest what sort of binding interactions could be involved
in holding acetylcholine to the active site.
2. The ester bond of acetylcholine is hydrolysed by
acetylcholinesterase. Suggest a mechanism by which the enzyme
catalyses this reaction.
3. Suggest how binding interactions might make acetylcholine
more susceptible to hydrolysis.
4. Structure I is an agonist which binds to the cholinergic
receptor and mimics the action of the natural ligand acetylcholine.
Structure II,...
Most questions answered within 3 hours.
-
Where is the error in this code sequence?
String s1 = "Hello";
String s2 = "ello";...
asked 10 months ago -
Financial data for Joel de Paris, Inc., for last year
follow:
Joel de Paris, Inc.
Balance...
asked 10 months ago -
Consider this reaction:
Al2(SO4)3 (aq)+ BaCl3
(aq) Al2Cl6 (aq)- +
3BaSO4(s) . What is the...
asked 10 months ago -
Suppose that Savneet is considering increasing her
recent random sample from 20 car rentals to 40...
asked 10 months ago -
Trucks arrive at an unloading terminal at an average rate of 120
per hour.
Trucks arrive...
asked 10 months ago -
Why are methanol and ethanol completely soluble in water while
octanol is not very little soluble....
asked 10 months ago -
A facilities manager at a university reads in a research report
that the mean amount of...
asked 10 months ago -
When the CuSO4 is rehydrated by adding water to the anhydrous
compound, is this an endothermic...
asked 10 months ago -
A ray of sunlight is passing from diamond into crown glass; the
angle of incidence is...
asked 10 months ago -
A block of mass 0.249 kg is placed on top of a light, vertical
spring of...
asked 10 months ago -
how do the kidneys compensate in the presences of acidosis
a) trigger hyperventilate
b) reserve acid...
asked 10 months ago -
Question 501 pts
The rental rate of capital to the firm increases. Which of the
following...
asked 10 months ago