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Which of the following defines a CpG island? clusters of CG-rich regions in intergenic regions in which the C is highly methy
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clusters of CG rich regions in intergenic regions in which the C is highly methylated.

many human genes have CpG islands near the promoter.

CpG islands are methylated in intragenic regions , mobile elements and repetitive sequence.

CpG islands within the transcription site are generally not methylated or relatively low level of methylation .

CpG island methylation of transcription start site is associated with stable long term silencing for example X- chromosome inacivation , imprinting ).

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