Question

research conditions that are caused by chromosomal abnormalities.

Answer 1

A kinondledge about chromosome > Chromosomes are presents is vous body cells these are organised package package of DNAL ONBcontain genes 'which gine a information about our body how u to devlope and functions Human body have 46 chisomosome mean 23 pais (23 from mather+23 father) A centromere present in each chromosome GHR techneq helpful for a picture of chromo- some. - 22 pair of chromosomes known as Autosomes. While a pair known as Sexchro- mosome In male - 22+ ny In female - 22+ na Yuldases determine Chresome.

noda chromosomes Disorder - these are two type Do Numerical ou 2 Structural w Numerical lisoseles occur when these change in the number of chromosome Enample so Trisomy, monosomy anel Isipidoidy. most numerical disorder or abnormalaties known as Down Syndrome trisomy 13, trisomy 18 Klinefelter Syndrome anel turneelsyner elrome. u Structural chromosome abnormalaties Kesult from breakages withi ina Chromosome the diffrence in number of copies of gene may lead to clinical diffrances Tén affected individual

chsomosomal deletion. its known as partial monosomies its occur when a piece of, or a section of |_chromosomal material is missing. When one break called terminal delation - When two breaks called cheerstital delatióis Enample - Cari-du-Chat syndrome and 229 11.2 delation syndrome. → Chromosomal duplicatais > L its known as partial trisomies its occur When a entra copy of a segment of chromuome: Ena-229.11.2 Duplicates sindrome: M ECP2 Duplicaliers S its occur when a chromosome breaks in two places and the resulting piece of DNA is reversed and reinserted in to the Chromosome. Escar paracentric Inverso y dicentric chromosome'- when abnormal fusion of two chromosome pieces.cach occupied a centromese: Ring chromosome! — When the ends of ball auns same Chromosome are deleted when the remaining ends to be sticky the thy Join togather make a ring shape. Esca. Ring chromosome synelcome.

3 Isochromosomes! — -- these are abnormal chromosomes with identical arms: two short parms and two long q arms. Both arms are from same side of centromere trar pallister -killian synchrome. - Unbalanced translocaties! - its occur when a chromosome seqment is_moreel from one chromosome ardother the overall ONA has been allered y Balanced translocations When a chromosome segment is mored from one chromosome to another in blanced translocatéis 's no delectable hel gain or loss of ONA. deletion Duplications Translocations GODID.