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Differences in gene dosage can be caused by regions of the genome that differ in copy...

Differences in gene dosage can be caused by regions of the genome that differ in copy number. Which of the following does not lead to variation in the number of copies of genes between individuals?

X chromosome inheritance

chromosomal duplications

reciprocal translocations

chromosomal deletions

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Answer #1

The chromosomal duplications lead to the formation of an extra chromosome which leads to the formation of the extra gene in the body and change in gene number. The chromosomal deletions leads to decrease in chromosome number and this will lead to the decrease in the gene that was supposed to present on the deleted segment of the chromosome. Translocations are known to affect the expression of genes at the breakpoints and in the case of unbalanced translocations, alter the gene copy number. The X chromosome inheritance does not lead to variation in the number of copies of genes between individuals.

The answer is A.

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