Question

QUESTION 3 Which of the following statement regarding the early events of DNA replication is true? O A. DnaA is the first protein to bind to the Origin of Replication. B. Origin of Replication is the protein that marks the region in the DNA where replication will begin. O C. DnaB is the helicase which unwinds the double helical structure of DNA. O D.DnaC has no activity but is responsible for brining DnaA to the Origin of Replication. O E. Two of the listed statements are correct. O F. Three of the listed statements are correct. . All of the listed statements are correct.

Answer 1

The correct answer is option E, i.e., two of the listed statements (A and C) are correct.

Statement B is incorrect as Origin of replication is not a protein rather it is a specific sequence in the genome or DNA where the replication begins.

Statement D is incorrect because DnaC assists the protein DnaB (helicase) loading instead of DnaA.

Sequence of events during early events of DNA replications linitiation) is as follows: 2 ) Binding of Dna A protein do Ori G lorigin of replication] [option A D $ 2.) Loading of DnaB (helicase) protein, DnaB binding Options " requires atp and Dnal. Helicase unwinds dsDNA. Dnal acts as helicase loader 3.) Binding of primase and synthesis of RNA primes. Polymerization by DNA polymerase.

Hence, two statements (A, C) re correct.