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In a case where there is a mutation that prevents the cofactor from binding to the repressor, and the result is that the oper
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The strains which are defective repressor which is positive one, are constitutive and makes the encoded enzyme with the help of lac operon though the inducer is absent

inducer are non inducible that is negative inducible do not show the interaction with strain repressor. Though the inducer will fail to bind the repressor be with the operator and helps in preventing expression of the operon even inducer is present.

This makes the option negative repressible correct.

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