Question

10) An inhibitor binds to the allosteric site of an enzyme. What is most likely to happen? a. The enzyme will be denatured b. The enyme will be natured C. The products will be created faster d. The rate of reaction will be slowed down 11) Match the organelles with their functions by placing letter (a-d) by each function: a. Ribosomes Package and ship proteins b. Golgi apparatus Store digestive enzymes C. Lysosomes Build proteins with instructions from RNA d. Vesicles Store and transport substances into and out of the cell 12) Angie was just diagnosed with cancer. She has a mutation on a tumor-suppressor gene. Normally, cells expressing these genes should: a. Undergo angiogenesis b. Prevent apoptosis C. Prevent damaged cells with damaged DNA from undergoing cell division d. All of the above

Answer 1

Q 10.

Ans. The correct option is d). The rate of the reaction will be slowed down.

Reason: Inhibitor when binds to the enzyme at the allosteric site, result in decreasing the rate of reaction. The inhibitor binds to the allosteric site and change the conformation of the enzyme in the active site, due to which substrate no longer can bind to the active site and lead to product conversion thus slow down the rate of reaction.

All other options are incorrect:

Neither the enzyme will be denatured nor will be natured, as there is no change in its native structure on inhibitor binding.

The products will not be created faster, as inhibitor slow down the reaction rate. Allosteric activator increases the rate of reaction, not he allosteric inhibitor.

Q 11.

b. (Golgi apparatus) Package and ship proteins.

Golgi apparatus package and ship protein molecules coming from the endoplasmic reticulum and then transport them from cis side to trans side of Golgi and further out of the cells

c. (Lysosome) Store digestive enzyme.

Lysosome are involved in cellular digestion as they house various hydrolytic enzymes.

a. (Ribosomes) Build proteins with instruction from RNA.

Ribosome are involved in protein synthesis within the cells by translating the mRNA into the protein.

d. (Vesicles) Store and transport substance into and out of the cell.

In vesicles the cell store and transports the substance, these vesicles are formed by the endoplasmic reticulum or Golgi apparatus.

Q 12.

The correct option is c). Prevent damaged cells with damaged DNA from undergoing cell division.

Reason: In normal state these gene product act as a gatekeeper of cell cycle preventing damaged cell undergoing further in the cell cycle. Thus tumor suppressor gene prevents damaged cells with damaged DNA from undergoing cell division.

All other options are incorrect:

The tumor suppressor gene has no role in angiogenesis in normal state.

In normal state they do not prevent apoptosis, they induce apoptosis of damaged cells in normal state.