Question

44. During DNA replication, the double helix is unwound, creating two single strands. One of these is called the strand, on which the progress of DNA Polymerase III is – 45. The other strand is called the strand, on which the synthesis is 16. During DNA replication, synthesis of a new sequence on the Leading Strand is continuous. Why is synthesis on the Lagging Strand discontinuous? 47. Generation of Okazaki fragments proceeds in three steps. Indicate which of the following is the correct sequence of these steps. a. Synthesis of replacement DNA b. removal of the RNA primer C. enzymatic joining of adjacent fragments a. Removal of the RNA primer b. synthesis of replacement DNA C. enzymatic joining of adjacent fragments b. removal of the RNA primer a. Enzymatic joining of adjacent fragments c. synthesis of replacement DNA b. synthesis of replacement DNA a. Enzymatic joining of adjacent fragment C. removal of the RNA primer a. Removal of the RNA primer b. enzymatic joining of adjacent fragments C. synthesis of replacement DNA

Answer 1

44. During DNA replication, the double helix is unwound, creating two single strands. One of these is called the Ledaing strand, on which the progress of DNA Polymerase III is Continous 45. The other strand is called the _strand, on which the synthesis is Discontinuous 16. During DNA replication, synthesis of a new sequence on the Leading Strand is continuous. Why is synthesis on the Lagging Strand discontinuous?

Answer- DNA polymerase only polymerizes in 5' to 3' direction. So the lagging strand is produced in small stretch called Okazaki fragments.

leading strand DNA Polymosiose VI Tagging DNA bolynocase IV DNA bolumerase

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