Question

Where would you find histones?

A. Part of the RNA polymerase complex that transcribes DNA.

B. In a virus, helping to "inject" foreign DNA into a cell.

C. Bound to an enhancer to regulate transcription.

D. Asscoiated with DNA to make chromatin.

What is the role of DNA ligase during DNA replication?

A. It unwinds the parental double helix.

B. It synthesizes RNA nucleotides to make a primer.

C. It joins lagging strand (Okazaki) fragments together.

D. It stabilizes the unwound parental DNA.

Why is the enzyme Primase (or RNA Primase) needed in DNA synthesis?

A. Primase joins Okazaki fragments together with RNA primers.

B. Because DNA replication is immediately followed by transcription.

C. Primase synthesizes the leading strand but not the lagging strand of DNA.

D. Because it is energetically more expensive to make DNA primers than RNA primers.

E. Because DNA polymerases cannot recognize single-stranded DNA to begin synthesizing the complementary strand.

Which of the following allows more than one type of protein to be produced from one gene?

A. alternative forms of chromatin remodeling

B. alternative forms of RNA splicing

C. miRNAs

D. control of the frequency of translation initiation

Answer 1

1.Answer is D. Associated with DNA to make chromatin.

Histones are proteins which are basic in nature. They are associated with DNA to condense it into chromatin.

All other options are wrong.

2. Answer is C. It joins lagging strand (Okazaki) fragments together.

During DNA replication DNA ligase connect Okazaki fragment

3. Answer is E. Because DNA polymerases cannot recognize single-stranded DNA to begin synthesizing the complementary strand.

Primase is a type of RNA polymerase, which synthesizes a primer so that DNA can replicate.

4. Answer is B. Alternative forms of RNA splicing

Alternative mRNA splicing is a process which results in a single gene which codes for multiple proteins. In this process exons (coding region of the DNA) are differentially joined or skipped, resulting in multiple protein isoforms.