Question

9. Which form of retinoblastoma must be achieved to promote cell cycle to the Sphase? A. dephosphorylated B. hypophosphorylated C. hyperphosphorylated D. hypophosphorylated or hyperphosphorylated depending on the type of the cell Describe the process of passing check point G1 during a cell cycle: 10. Which proteins are involved in creation of apoptosomes? A. Caspase 8 and caspase 9 B. Caspase 9 and cytochrome C only C. Caspase 9 and Apaf-1 only D. Caspase 9, cytochrome C and Apaf-1 Describe the role of Fas (CD95) in initiation of cell apoptosis:

Please answer these questions correctly!

Answer 1

stion c is correct Hyperphosphorylated forem must be acheived for transition from si to s phase of cell cycle. he active, un or hybo bhos phoxylated form of the pRb Hotein bỉnd transuiftion factor Edf and crepuesses gene transciption which is vequired for transition from ci to s phase when PRO is phosphorylated in many site it Tead its transition from qi tos. So Obtion c correct, Ans Go checkpoint Check for cell Size , nutrients availability , Growth factor and ONA damage if any Qi to šº transition occurs when these factors are normal Gils checkpoint ensures there is no damage in DNA. Rb protein p53 play oeole awresting the cell in G. if DNA damage occur for Eq Cyclin -CDK complexes oregulate pRBIE&F activity On Early and Mid 9 prb is un phosphorylated or Shorylated but when E-cok2 Phosphorylated pRb cleave e Hyperphosphorylale lead Eaf to that become & as Otranscription factor induces transcription far s-phase gene. act