Answer : D. No, the offspring of I-1 and I-2 contradict an autosomal dominant inheritance.
Explanation :
Traits that exhibit dominant gene action are = 1. Affected individuals have atleast one affected parent. 2. Phenotype will appear on every generation. 3. Two unaffected parents only have unaffected offspring
In this case I-1 and I-2 are not affected but they're offspring are affected so the pedigree is not caused by an autosomal dominant disease.
Could the characteristic followed in the pedigree in the attachment be caused by an autosomal dominant...
a.) Before individual II-2 had an affected
son, this family believed the condition followed a dominant mode of
inheritance. Why does the phenotype of III-1 support a
recessive rather than a dominant mode of inheritance?
b.) Could the mode of inheritance actually be dominant? Explain
using appropriate genetic terms.
c.) In order to better understand the risk of passing this
condition on to additional offspring, individual II-2 sought
genetic counseling which resulted in the drawing of this pedigree.
This action makes...
The autosomal dominant disease nail-patella syndrome is linked to the ABO blood type locus. The pedigree below shows a family in which some individuals are affected by nail-patella syndrome. The blood type of each individual is given as capital letters above each individual symbol. The image can also be downloaded here: Figure B Final.pdf A B - 2 AB II 2 A B B B A B B A 2 3 4 5 6 7 8 Can you explain this...
. O . Using Pedigrees to hypothesize patterns of inheritance 5. For each of the pedigree charts on the following page, determine which pattern of inheritance most likely explains the observed pattern of traits in the family shown. Observe the general patterns in the pedigree charts on the following page o males vs females? parents with disease? Compare these patterns with the clues on the previous page to hypothesize a pattern of inheritance Based on this pattern of inheritance, use...
The conclusions about inheritance (above) can be used to help analyze pedigrees. For each pedigree below, tell if the trait can be autosomal dominant, autosomal recessive, and X-linked recessive. If the pedigree cannot fit a mode of inheritance, tell why. Record your answers in the table on the next page. Pedigree A 2 3 o.a. 9 10 12 (13 14 ad ada 15 16 Xx 20 aa ia ha Pedigree B 910 11 12 14 a ta da Enter either...
QUESTION 3 If the characteristic depicted in the pedigree below is subject to complete penetrance, which of the following modes of inheritance are possible? 3 4 1 2 Y linked Mitochondrial X linked recessive Autosomal recessive QUESTION 4 5 p. If the characteristic depicted in the pedigree below is subject to complete penetrance, what is the genotype of individual II-3? 2 2 3 Shop N 1 2 3 AA, homozygous dominant aa, homozygous recessive Aa, heterozygous QUESTION 5 If the...
The autosomal dominant disease
nail-patella syndrome is linked to the ABO blood type locus. The
pedigree below shows a family in which some individuals are
affected by nail-patella syndrome. The blood type of each
individual is given as capital letters above each individual
symbol.
Can you explain this pattern without a cross-over event? If not
in which individual did the cross-over occur?
А. B — 1 2 АВ 0 ІІ 1 2 A B B B A B B A...
The mode of inheritance for this pedigree is autosomal
dominant.
If I-1 and II-2 were to have another child, what is the
probability that their child would express the trait? Explain.
1 1 N II 1 3 4 5 6 N = 1 2 3 4 5 6
What is the mode of inheritance for hypercholesterolemia?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible
----------------------------------------------------------------
What is the mode of inheritance for Hunter's syndrome?
a.
Autosomal dominant
b.
Autosomal recessive
c.
X-linked dominant
d.
X-linked recessive
e.
More than one of the above are possible.
------------------------------------------------------------
What is the genotype for individual II-3 at the
hypercholesterolemia locus (dominant allele is denoted by H,
recessive allele...
QUESTION 9 5 pe If the characteristic depicted in the pedigree below is rare and subject to complete penetrance, it is likely to be X-linked recessive? 5 6 7 -OOO No, because individuals ll-2 and 11-4 are not affected No, because individuals 111-4 and III-6 are not affected Yes, because individuals III-4 and III-6 are not affected Yes, because only females are affected in generation 11 1. The gene for cystic fibrosis (normal dominant allele CF and abnormal recessive allele...
The possible modes of inheritance are autosomal dominant autosomal recessive X-linked recessive mitochondrial inheritance || ITQ ? 11 2 3 4 23 TO O | 1 2 3 | | O ■ 2 3 2 3 4 5 Question 1 (12 marks) For the following pedigrees i. identify the most likely mode of inheritance, and ii. describe 2 features that fit with that mode of inheritance. 1 mark each 2 marks each The possible modes of inheritance are autosomal dominant...