Question

22. What are the roles of Dicer and RISC in the function of miRNAs? Dicer RISC 23. Describe the concepts of primary, secondary, tertiary and quaternary protein structure 24. Here is a short sequence of codons. AUG CAU UGU UUU Write out the amino acids this sequence of codons encodes. Now add an insertion mutation of your choosing in the first codon and write out the new mutant sequence. What are the first four amino acids encoded by this mutant stretch of mRNA? Connect the concepts: two ways of termination of transcription the genetic code is prevents transcription of a specific gene genes that are always expressed can form base pairs with both A and G binds -35 and -10 consensus sequences prevents translation of a specific transcript bonds that hold together amino acids in a polypeptide has binding sites for both tRNAs and amino acids large complexes involved in protein synthesis ribosomal small subunit rRNA in prokaryotes added to the 3' end of mRNA in eukaryotes phosphorylating this begins elongation ribosomal small subunit rRNA in eukaryotes the aminoacyl site of the ribosome the peptidyl site of the ribosome added to 5' end of mRNA in eukaryotes the exit site of the ribosome comprise the spliceosome polymerase that transcribes siRNAs and snRNPS 5 Cap Poly A tail sigma factor intrinsic and tho dependent Carboxy terminal domain SnRNPs miRNAs SiRNAs constitutive RNA polymerase III Peptide bonds Nonoverlapping Amino acid RNA synthetases Uriacil Ribosomes 188 105 Ae Psite 10. 13 14 15 18

Answer 1

as per HomeworkLib guidelines we can answer only one question in a time limit.feel Free to ask for further explanation

microRNA (miRNA ) function in RNA silencing or RNA interference. MiRNA is a small Non-coding RNA molecule. Role of Dicer and RISG in the function of miRNA are as follow- Role of Dicer - The Enzyme Dicer is responsible for the cleaverge of Double staanded RNA COS-RNA) in to small interfering RNA Role of RISC – RNA induced Silencing Complex (RISC) is an specific Ribonucleobootein. The small interfering RNA ar single stoonded micro - RNA act as a Template for RISC To recognize messenger RNA (m-RNA) and Prevent The Translation process. This is known as RNA silencing.