Question

Figure for Q-8 and9

Q-8 and 9: The following figure is about T cell images exhibiting the distribution of the specific protein (Q-8: ). To visualize the distribution of (Q-8), pure T cells were cultivated in a cell-culture petri dish and then untreated or treated with (Q-9: ). The cells were left untreated (A), or treated with (Q-9) and incubated in an optimal condition for 10 min (B), 30 min (C), 1 hour (D), 2 hours (E), 4 hours (F). 6 hours (G), or 24 hours (H) . The cells were then stained with the antibody recognizing the protein (Q-8).

As a result, these cell images (Figure for Q-8 and 9) show that (Q-8) was distributed throughout the cell when the cells were treated/stimulated with (Q-9).

Q-8: Find a correct name of the molecule that is best relevant to Q-8.

A. T-cell receptor complex,

B. MHC class I and II molecules

C. Akt

D. Phospholipase gamma (PLC?),

E. Protein kinase C-?

Q-9: Find a correct name of the molecule that is best relevant to Q-9.

A. FTY720 (Fingolimod),

B. Infliximab,

C. Asciminib

D. Pyimo-morephosin acetate

E. Phorbol myristate acetate,

Please choose one answer for Question 8 & 9 (Q-8 & Q-9) and explain why. Fill in the blanks above with the correct answer provided for question 8 and 9 as indicated above.

Answer 1

8). Option B is correct.

Explanation: MHC class I or II molecules are only found on the antigen-presenting cells. As in the question the cells were stained with the antibody recognizing the protein. Only MHC molecules can recognize the protein from the antigen-presenting cells.

9). Option B is correct.

Infliximab is the only chimeric monoclonal antibody that works as a chemical messenger and stimulates the treated cells and shows an immune response.