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Part B. Stes of protein synthesis n the All proteins are thesized by boomes in the Som m es o endomembrane system or pass thr
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ER proteins, DNA polymerase, Lysosomal enzyme and Insulin.

Free ribosomes synthesize proteins functioning in the cytosol, while bound ribosomes synthesize proteins that either go through endomembrane system or secreted out of the cell. ER proteins, DNA polymerase or Lysosomal proteins have to go through endomembrane system. They need to be processed further so they can reach their target, hence they are synthesized by bound ribosomes, so the processing can take place in the endoplasmic reticulum. Insulin is a protein hormone which needs to be secreted out of the cell, hence it is also synthesized by bound ribosomes. Actin and ribosomal proteins, on the other hand are cytosolic proteins and can be synthesized by free ribosomes.

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