A human embryonic stem cell has been tested and verified to be pluripotent. What are some...
- A human embryonic stem cell has been tested and verified to be pluripotent. What are some reasonable expectations if we artificially double the OCT4 gene expression? (2 pts)
- What if the cell’s normal Oct4 expression is reduced by 0.5?
Homework Answers
A) oct 4 is a homodomain binding protein and it function as a cell renewal and undifferentiated marker. If embryonic cell has more Oct 4 expression it's means that the embryonic stem cell will replenish themselves .they will not differentiate.
2)if Oct 4 level reduces , then the cells will be differentiated and will go further towards differentiation. if cell had more expression of Oct 4 then it will go to dedifferentiation.
Thank you
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