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10 11 17 18 19 20 5- The above diagram is a representation of the Karyotype of a patient with a chromosomal abnormality. Base

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From the above karyotype, we can see that one copy of chromosome 15 is entirely missing (monosomy). Monosomy may result from non-disjunction or chromosomal lag. In both of these events, homologous chromosomes or sister chromatids fail to separate properly during cell division.

The disease that results from the loss of a copy of chromosome 15 is called as Prader-Willi syndrome .

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