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What are the critical functions of ECM? What is Anchorage Dependence?

  1. What are the critical functions of ECM?
  2. What is Anchorage Dependence?
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Answer #1

1. First, we will see what is ECM (Extra Cellular Matrix), " It is a 3-dimensional network of collagen, enzyme, and glycoproteins which is responsible for structural and biochemical support for cells.

2. The function of ECM is to support the cells to bond together ad perform the no. of functions such as adhesion, migration, proliferation, differentiation, and muscle fiber force transmission. If there will be any change in ECM structure it causes fibrosis, muscle aging, myopathies.

3. Anchorage dependence is nothing but the cell required support to adhere to other cells for survival if it will not get any support these cells may die.

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