Question

please answer and show work for stepwise synthesis and other questions.

1. Provide a stepwise synthesis for the dipeptide Ser-Phe. Draw all steps including protecting groups. H2N-CH-C-OH H2N-CH-C-OH CH2 Phe Ser 2. Using ethyl 3-methylbutanoate as your only source of carbon and using any other reagents necessary, propose a stepwise synthesis for the following conversion. 3. Provide the reagents necessary to carry out the following conversion. 4. Provide the structures of the products in each step of the following reaction sequence.

Answer 1

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hy we use two type of protecting groups . iy fore amino acids, we use to Butyloxy carbonge (Boc) all for Carbonala aid = we convert no into ester C Carbonate , Since en -an amino a cielo two type of .. bunctional groups are present c so out of two one is protected and other one is made to react in order to obtain our desirable dipeptide In-ch-Grohe Bach -cn-c-oh H-protection N-protection Phe h -ch-C-on c-protection S1 = H – – az 애 04 son e Boc Hoito-oh soc oc 0 -"C-on-en-c-och H 1 3-go 952 см BOHN-CH- & sco • ZI com Hydrolysis (dipeptide)