a.Several DNA motifs in proximal promoters are essential for the commencement of transcription from particular genes....
a.Several DNA motifs in proximal promoters are essential for the commencement of transcription from particular genes. What are two of these motifs and how do they function to promote transcription?
b.How do “basal” or “general” transcription factors compare with tissue- or cell-type specific transcription factors?
Homework Answers
a) Motifs are short, recurring patterns in DNA are presume to have a biological function. They indicated sequence specific binding site for protein, such as NUCLEASES and TRANSCRIPTION FACTOR ( TF).
b) in comparison of prokaryotes, the eukaryotes and in humans there is an extra step. Rna polymerase can attach to pthe promotor only with the help of protein called basal (general) TF. They are part of cells core transcription toolkit needed for transcription of any gene.
However may TF not the general kind. Instead there is a large class of TF that control the expression of specific individual genes. For instance, a TF might activated only a set of gene needed a certain neuron.
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