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list the seven major functions of the complement cascade

list the seven major functions of the complement cascade

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Answer #1

1) Bacteriolysis and cytolysis:- Complement mediates bacterial cell membrane damage and results in bacteriolysis and cytolysis.

2) Amplification of inflammatory response:- C3a and C5a leads to degranulation of mast cells leading to release of histamine and increase in vascular permeability.

Hypersensitivity Reaction:- Type 3 and Type of hypersensitivity reactions.

Endotoxin Shock'- C3 activation leads to thrombocytopenia and DIC.

Immune Adherence

Opsonization

Autoimmune Disease.

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