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can x-linked recessive traits skip generations in pedigrees?

can x-linked recessive traits skip generations in pedigrees?

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Yes, X-linked recessive traits can often skip generations in pedigrees since the trait is always passed in a criss-cross fashion, i.e., an affected father (XY) will have an unaffected carrier daughter who will pass on the trait to son (XY) in the 3rd generation, thus phenotypic expression of the trait has skipped the 2nd generation. Similarly if an carrier female (XX) marries an unaffected male, then (XY) also, there is only 25% probability of their child carrying the trait, thus it is quite possible for the trait to skip generation. In fact, one of the identifying features of recessive traits is that it skips expression in generations in pedigrees, whereas a dominant trait will always be expressed in all generations across the pedigree.

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