X-linked hypophosphatemia (XLH) is due to a rare X-linked dominant form of rickets. A man with XLH marries a healthy woman and they have a son with XLH. The MOST LIKELY explanation for this occurring is:
A. During spermatogenesis in the father, Meiosis I non-disjunction of the X chromosome generated a disomic sperm.
B. During spermatogenesis in the father, Meiosis II non-disjunction of the X chromosome resulted in a disomic sperm.
C. During oogenesis in the mother, Meiosis I non-disjunction of the X chromosome generated a nullosomic egg.
D. During spermatogenesis in the father, Meiosis II non-disjunction of the Y chromosome generated a disomic sperm.
E. During oogenesis in the mother, Meiosis I non-disjunction of the X chromosome created a disomic egg.
The correct answer is-
C. During oogenesis in the mother, meiosis I non-disjunction of the X chromosome generated a nullosomic egg.
X-linked hypophosphatemia (XLH) is due to a rare X-linked dominant form of rickets. A man with...
Color-blindness is an X-linked recessive condition. A man with normal vision and a woman who is color-blind have a child with Turner Syndrome. This child has normal vision. Where did the non-disjunction occur? In meiosis I of the mother In meiosis II of the mother In meiosis I of the father In meiosis II of the father In either meiosis I or II of the mother.
Two normal parents have a son with hemophilia (an X-linked recessive disorder) that also has Klinefelter Syndrome. a. Write out the cross as described above illustrating the genotypes and phenotypes of the parents and child. b. Did the non-disjunction event occur in the mother, the father, or could have occurred in either of the two parents? c. Did the nondisjunction event occur during meiosis I, meiosis II, or could it have occurred in either division during meiosis.
An antigen found on red blood cells, Xg, is encoded by an
X-linked allele (Xa) that is dominant over an allele for the
absence of the antigen (X–). Scientists studied the inheritance of
these X-linked alleles in children with chromosome abnormalities to
determine where nondisjunction of the sex chromosomes occurred.
Match the genotypes of the parents and offspring to the parent
and cell division stage in which the nondisjunction must have
occurred. Shown as parent × parent = child.
Nondisjunction...
Genetics question: An X-linked dominant allele causes hypophosphatemia in humans. A man with hypophosphatemia marries a normal woman. What proportion of their sons will have hypophosphatemia? Please show work. Thank you!
In a routine prenatal screen, a clinical researcher finds that
the karyotype of cells derived from a fetus shows potential trisomy
(one of the chromosomes is present in 3 copies). It is not clear
whether the extra chromosome is chromosome 6 or 7 (because
chromosome 6 and 7 are quite similar in a simple chromosome spread
analysis). To determine whether the extra chromosome is chromosome
6 or 7, the researcher performs polymerase chain reaction followed
by RFLP analysis using DNA...
Two normal parents have a daughter with hemophilia (an X-linked recessive disorder) that also has Turner Syndrome. a. Write out the cross as described above illustrating the genotypes and phenotypes of the parents and child. b. Did the non-disjunction event occur in the mother, the father, or could have occurred in either of the two parents? Did the nondisjunction event occur during meiosis I, meiosis II, or could it have occurred in either division during meiosis.
Vitamin D-resistant rickets is a genetic condition inherited as X-linked dominant. A husband has this Vitamin D-resistant rickets but his wife does not. What is the probability that their first child will be a: (4 pts) a) normal son? b) normal daughter? c) son with Vitamin D-resistant rickets? d) daughter with Vitamin D-resistant rickets DHU The eye is an example of an organ that develops from a complex series of developmental events, controlled and influenced by many genes. This process...
In man, normal pigmentation (A) is autosomal dominant to albino (a) and hemohilia (Xh) is sex-linked recessive to normal (XH). An albino, non-hemophilic man marries a normally pigmented, non-hemophilic woman whose father was hemophilic and whose mother was an albino. What are the genotypes of the man and woman? What phenotypes are possible in their children and in what proportions?
Colorblindness and Hemophilia A are X-linked recessive conditions. A woman heterozygous for hemophila mutation and a colorblind man have a son who is haemophilic and has Klinefelter's syndrome (XXY). Which of the following nondisjunction events is the most compatible with the situation described? Please provide an explanation a. meiosis I, mother b. meiosis II, mother c. meiosis I, father d. meiosis II, father e. a and b
10. In humans Wiskott–Aldrich syndrome (WAS) is a rare sex-linked recessive disease characterized by eczema, thrombocytopenia (low platelet count), immune deficiency, and bloody diarrhea. This disease is due to a sex-linked recessive allele. a. Examine the statement below. Is this statement true or false? Why? Explain. Boys usually inherit sex-linked recessive disorders from their fathers. Sarah is healthy and but her brother has WAS. Her mother and father both have healthy phenotypes. Sarah marries Fred, a healthy man without WAS....