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What are the consequences of the missense mutations in BCR-ABLT315I and BRAFV600E? A. Both missense mutations...

What are the consequences of the missense mutations in BCR-ABLT315I and BRAFV600E?

A. Both missense mutations convert drug-sensitive oncogenes to drug-resistant oncogenes.

B. Both missense mutations convert two proto-oncogenes to oncogenes.

C. Both missense mutations generate constitutively active tyrosine oncokinases.

D. BCR-ABLT315I converts a drug-sensitive oncogene to a drug-resistant oncogene. BRAFV600E converts a proto-oncogene to an oncogene.

E. Both missense mutations convert drug-sensitive oncogenes to drug-resistant oncogenes.

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