Question

A GPI anchored protein will finally reside where A) In the Golgi B) In the ER...

A GPI anchored protein will finally reside where

A) In the Golgi

B) In the ER

C) In the plasma membrane facing the cytosol

D) In the plasma membrane facing the extracellular environment

E) In the lysosome

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Answer #1

Answer=(D)In the plasma membrane facing the extracellular environment.

Explanation-

Membrane proteins which are covalently bound to lipid molecules are called lipid-linked(or lipid anchored) membrane proteins.They form covalent attachment.

A gylcosylphosphatidylinositol molecule(GPI) attaches to the C-terminal amino acid via an amide linkage.Proteoglycans is the example of GPI anchored protein.

Now consider other option-

Option A and Option E are incorrect because Golgi and lysosome are not associated with GPI anchored protein.

Option B is incorrect because only synthesis is takes place in ER.

Option C is incorrect because GPI anchored proteins occur on the exoplasmic face of the plasma membrane.

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