37. In the binding of molecules, how are the MHCs different that Igs? How do superantigens bind to MHCs?
37. In the binding of molecules, how are the MHCs different that Igs? How do superantigens...
Why are MHC molecules able to bind a variety of peptides? 1. the peptide-binding groove of a specific MHC molecule can bind several peptides simultaneously 2. The MHC genes undergo somatic recombination to produce thousands of MHC molecule variants 3. MHC bind very loosely and transiently to peptide antigens, so a wide variety of peptide antigens can bind any specific MHC molecule 4. a small number of amino acids in the peptide antigen bind specifically to complementary pockets in the...
Receptors are capable of binding different chemical molecules, having impact on potential downstream signalling. Within this context, differentiate between endogenous hormones, agonists, and antagonists for a NUCLEAR RECEPTOR.
multiple choice questions
Molecules that are both hydrophobic and hydrophilic are The hyperbolic binding curve of myoglobin differs from the sigmoidal curve of hemoglobin in that the hyperbolic curve What type of bond links the monomers of a polysaccharide? An enzyme inhibitor that does not bind to the active site is a (an) Examine the cyclic D-monosaccharide shown below. The linear form of this monosaccharide must be a/an The catalytic triad of Trypsin and other serine proteases consists of
2. How do allosteric regulators affect their target enzymes? o By binding to the enzyme's active site and causing a conformational change in the enzyme By binding to a site other than the active site and causing a conformational change in the enzyme C) By inducing amino acid side chain substitutions at a site other than the attive site, causing a conformational change in the en By binding to the enzyme's active site and blocking the binding of substrate molecules...
The hunchback gene has an enhancer containing 3 binding sites for the transcription factor Bicoid. How could the loss of a single DNA binding site -leaving the 2 others intact- act to reduce gene expression of hunchback by more than 1/3 ? A. Bound Bicoid transcription factor molecules interact antagonistically to cause maximal gene expression B. Bound Bicoid transcription factor molecules interact additively to cause maximal gene expression C. Bicoid does not bind to the hunchback enhancer D. Bound Bicoid...
How is the mechanism by which eukaryotic repressors function different from that by which prokaryotic repressors function? 1. Bacterial repressors bind to operators and RNA polymerase simultaneously, inhibiting polymerase activity. 2. Eukaryotic repressors bind to silencers and RNA polymerase simultaneously, inhibiting polymerase activity. 3. Bacterial repressors directly block RNA polymerase from binding to the promoter. 4. Eukaryotic repressors directly block RNA polymerase from binding to the promoter. 5. The mechanisms of bacterial repressors and eukaryotic repressors and highly conserved and...
Compare and contrast how non-specific and specific interactions contribute to the binding of target molecules, using serine proteases and bZip proteins as examples. Illustrate your answer with structures and diagrams? (2 page Min)
The binding difference between carbon and oxygen molecules is the same as 2, the binding energy is 118 kcal/mole and the carbon is 144 kcal/mole. Why is carbon larger than oxygen? please explain based on MO theoory
Differentiate between chlorophyll a and chlorophyll b. How are the two molecules structurally different and how do their absorption spectra differ?
1. Consider a dilute solution of molecules at fixed temperature T. These molecules have access to a surface that has a total of B binding sites where molecules can bind. To count states in this system, we will divide space into small cells that each can hold a single molecule. There are a total of B cells that have a binding site, and a total of M cells that do not have binding sites. The overall number of cells is...