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Which of the following would be of LEAST value in DNA profiling? A) mitotyping B) analysis...

Which of the following would be of LEAST value in DNA profiling?

A) mitotyping

B) analysis of SNPs (single nucleotide polymorphisms)

C) STR (short tandem repeat) analysis

D) sequencing blood group alleles

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Answer #1

Option D

DNA profiling is used to determine relationship between individuals on the basis of certain sequences present in their genome.

In mitotyping, mitochondrial DNA of different individuals compared. This is a particular importance because mitochondrial DNA is highly conserved between different species and between different individuals of same species.

Single nucleotide polymorphism is used to determine single changes in nucleotide of a gene.

Short tandem repeats are repetitive sequences which are present in all the individuals but their number varies.

Blood grouping will be the least valuable in DNA profiling because it is subject to change.

By determining relationships between individuals and species, we always use conserved sequences so that it is easy for us to compare the sequences and determine where the change has occurred.

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