Question

In Great Apes, the metabolic disorder causing lipoprotein lipase deficiency (LPL) is attributable to a defective allele at a single gene locus. There are only two alleles known at this locus, Pand Z. Heterozygotes and homozygous PP individuals show no symptoms of disease. Homozygous ZZindividuals suffer severe effects.Suppose a breeding population of 100 genetically modified apes lives in a special zoo (a very large and well-funded zoo); 25 of the apes are known to have the LPL disorder, while 75 of the apes show no signs of the disorder. However, all the apes are given medications and special diets that completely counteract the effects of the LPL disorder so that individuals with the disorder suffer no effects of the disease. In addition, the apes have been genetically modified so that they all reproduce once and at the same time and their generations do not overlap; put another way, subsequent generations completely replace previous generations, so that once offspring reach sexual maturity, no parent is still alive.

In the zoo, what is the relative fitness of the genotypes containing Palleles (PPor PZ)? 4)

In the zoo, what is the relative fitness of the phenotype associated with a homozygous genotype?

Answer 1