Question

Becker muscular dystrophy is caused by a rare sex-linked allele and usually affects only males. Victims of the disease become progressively weaker starting early in life. If your mother’s brother (your uncle) had Becker dystrophy, what is the probability that you received the allele? What is the probability that if your uncle had a son, that the son would have the allele?

Answer 1

Ans: Each son born to a woman with a dystrophin mutation on one of her two 'x' chromosome has a 50% chance of inheriting the flawed Gene and having Becker muscular dystrophy. Patient with BMD live at least 30 years. Boys have only one x chromosome but girls have two. Girls can also have symtoms but in general they are less severe than in boys.only it get from parents not from Uncle.

In inheriting muscular dystrophy you have two copies of every Gene ( with the exception of the sex chromosome) you inherit a copy from one parent, and the other copy from the other parent. If one or both of your parents has a mutated Gene that causes MD.