What happens when a microtubule loses its GTP cap? Why?
What happens when a microtubule loses its GTP cap? Why?
Homework Answers
Microtubules are polymeric cytoskeletal elements formed from the α- and β-tubulin monomers. They play an important role in cell cycle progression. The regulation of their assembly and disassembly is dependent largely on the GTP molecules.The GTP cap is crucial for polymerization of microtubules. The growing end of microtubules contains a GTP cap. Shortly after the addition of a GTP molecule during polymerization, hydrolysis occurs, changing GTP into GDP and Pi. If the cap is lost or removed, the microtubule destabilizes and starts shrinking in length.
What happens to a microtubule that loses its "GTP cap"? Nothing. It begins to assemble. It...
What happens to a microtubule that loses its "GTP cap"? Nothing. It begins to assemble. It begins to de-assemble.
How does a GTP cap prevent a microtubule from falling apart, and how does a microtubule...
How does a GTP cap prevent a microtubule from falling apart, and how does a microtubule lose its GTP cap? If the rate of adding GTP-heterodimers to a microtubule is greater than the rate of GTP hydrolysis, then will the microtubule continue growing or fall apart? Explain your answere. Assume that in a normal cell the average length of microtubule reaches before falling apart is 8 micrometers. Imagine a cell with mutant B-tubulin that catalyzes hydrolysis at a rate slower...
Consider a mutation in tubulin that alters how tubulin changes its conformation after GTP hydrolysis. More...
Consider a mutation in tubulin that alters how tubulin changes its conformation after GTP hydrolysis. More specifically, the mutation makes tubulin "stiffer" after GTP hydrolysis, such that the tubulin does not transition as quickly between the straight and curved conformations. How would microtubule dynamics be affected by this mutation? Select all that apply. Question 5 options: a) Microtubules will grow faster (the net growth rate increases). b) Microtubules will shrink more slowly after a catastrophe (the "post-catastrophe shrinkage rate" is...
1.) What happens to the translation initiation complex before the ribosomal subunit can be added? 2.)...
1.) What happens to the translation initiation complex before the ribosomal subunit can be added? 2.) What are two ways aminoacyl tRNA synthetase ensures proper pairing between tRNA and amino acid? 3.) What stages of transcription or translation require GTP hydrolysis? 4.) When only non-hydrolyzable GTP tubulin dimers are available, how this affect the shrinking of microtubule filament?
Please explain. Dynamic instability causes microtubules to either grow or shrink rapidly. Consider an individual microtubule...
Please explain.
Dynamic instability causes microtubules to either grow or shrink rapidly. Consider an individual microtubule that is i its growing phase: What causes the microtubule to stop growing and to rapidly shrink/depolymerize? 1. Concentration of free GDP-tubulin in 2. Concentration of free GTP-tubulin in the 3. Rate of addition of GTP-tubulin to the A. 1 and 4 B" 2 and 3 C. 1, 3 and 4 D. 2, 4 and 5 E. 2, 3 and 5 the solution increases...
What Does 200 Million Percent Inflation Look Like? Here’s What Happens When The Central Bank Loses...
What Does 200 Million Percent Inflation Look Like? Here’s What Happens When The Central Bank Loses Control. Zimbabwe has been facing 200 million percent inflation. A loaf of bread is a billion Zimbabwe dollars. As you might expect, the US dollar is in short supply there and people are hurting. It relates to sanctions imposed by the West in response to corruption at the highest level of government. On Nov, 21, 2017, Robert Mugabe, the president who ruled Zimbabwe for...
I just want to see if the answers are right, so for 1a. since the microtubule...
I just want to see if the answers are right, so for 1a. since
the microtubule is in a cell that's in G0, would there be no
movement since everything stops in G0 phase? Or are the
microtubules continously depolymerizing/polymerizing at a constant
rate?
For 1b. I said the same thing since the cell is in G0 phase then
it wouldn't matter if it was microtubule treadmilling, it wouldn't
be moving.
1c. I'm not sure what exactly would happen
I'm...
what happens to resistance of a series when light bulbs are added to the series? why...
what happens to resistance of a series when light bulbs are added to the series? why what happens to the overall resistance of a parellel circuit when light bulb are added? why?
What happens to the WBC count when you have an infection? Why?
What happens to the WBC count when you have an infection? Why?
what happens to the Phenol Red broth when acids is produced? explain why
what happens to the Phenol Red broth when acids is produced? explain why
Please explain.
Dynamic instability causes microtubules to either grow or shrink rapidly. Consider an individual microtubule that is i its growing phase: What causes the microtubule to stop growing and to rapidly shrink/depolymerize? 1. Concentration of free GDP-tubulin in 2. Concentration of free GTP-tubulin in the 3. Rate of addition of GTP-tubulin to the A. 1 and 4 B" 2 and 3 C. 1, 3 and 4 D. 2, 4 and 5 E. 2, 3 and 5 the solution increases...
I just want to see if the answers are right, so for 1a. since
the microtubule is in a cell that's in G0, would there be no
movement since everything stops in G0 phase? Or are the
microtubules continously depolymerizing/polymerizing at a constant
rate?
For 1b. I said the same thing since the cell is in G0 phase then
it wouldn't matter if it was microtubule treadmilling, it wouldn't
be moving.
1c. I'm not sure what exactly would happen
I'm...
Most questions answered within 3 hours.
-
Where is the error in this code sequence?
String s1 = "Hello";
String s2 = "ello";...
asked 10 months ago -
Financial data for Joel de Paris, Inc., for last year
follow:
Joel de Paris, Inc.
Balance...
asked 10 months ago -
Consider this reaction:
Al2(SO4)3 (aq)+ BaCl3
(aq) Al2Cl6 (aq)- +
3BaSO4(s) . What is the...
asked 10 months ago -
Suppose that Savneet is considering increasing her
recent random sample from 20 car rentals to 40...
asked 10 months ago -
Trucks arrive at an unloading terminal at an average rate of 120
per hour.
Trucks arrive...
asked 10 months ago -
Why are methanol and ethanol completely soluble in water while
octanol is not very little soluble....
asked 10 months ago -
A facilities manager at a university reads in a research report
that the mean amount of...
asked 10 months ago -
When the CuSO4 is rehydrated by adding water to the anhydrous
compound, is this an endothermic...
asked 10 months ago -
A ray of sunlight is passing from diamond into crown glass; the
angle of incidence is...
asked 10 months ago -
A block of mass 0.249 kg is placed on top of a light, vertical
spring of...
asked 10 months ago -
how do the kidneys compensate in the presences of acidosis
a) trigger hyperventilate
b) reserve acid...
asked 10 months ago -
Question 501 pts
The rental rate of capital to the firm increases. Which of the
following...
asked 10 months ago