Hemophilia is an x-linked recessive trait. In a population of 2000 people, 4 women have hemophilia, 30 men have hemophilia, and 80 are carriers of the disorder. What is the frequency of the hemophilia allele? (Assume the population is 50% men and 50% women.)
| a. |
0.038 |
|
| b. |
0.059 |
|
| c. |
0.033 |
|
| d. |
0.057 |
|
| e. |
0.039 |
Answer:
e. 0.039
Explanation:
4 hemophilic women = 8 hemophilic alleles
30 hemophilic men = 30 hemophilic alleles
80 carrieres = 80 normal alleles and 80 hemophilic alleles
Remaining individuals are normal = 2000 – 114 = 1886
943 men = 943 normal alleles
943 women = 943*2 = 1886 normal alleles
Total alleles = 8+30+80+80+943+1886=3027
Total hemophilic alleles = 8+30+80 = 118
Frequency of hemophilic allele = 118/3027 = 0.039
Hemophilia is an x-linked recessive trait. In a population of 2000 people, 4 women have hemophilia, 30...
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