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Please show the reaction catalyzed by the enzyme in Medium-chain acyl-CoA dehydrogenase.

Please show the reaction catalyzed by the enzyme in Medium-chain acyl-CoA dehydrogenase.

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Answer #1

Medium-chain acyl-CoA dehydrogenase is a mitochondrial beta oxidation enzyme that catalyzes the alpha beta dehydrogenation of the corresponding medium chain acyl CoA by FAD, which gets reduced.

Medium-chain acyl-CoA + Electron transfer flavoprotein <=====> Medium-chain trans-2,3-dehydroacyl-CoA + reduced electron transfer flavoprotein

The reduced form of Medium chain acyl CoA dehydrogenase is reoxidized in the oxidative half reaction by electron transferring flavoprotein from which electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis.

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