describe cumulative and gradual effect of training on gene expression, mRNA levels and protein syntheses
Answer-
describe cumulative and gradual effect of training on gene expression, mRNA levels and protein syntheses
4. (2pts) Which of the following is true concerning expression levels of the BIS gene in cells expressing miR-5? BIS gene expression is increased in these cells BIS gene expression is decreased in these cells BIS gene expression remains unchanged in cells expressing miR-5 Transcription initiation of BIS is negatively regulated Question 4 2 pts 5.(2pts) Which of the following are true of p101 expression in these cells? o increased amounts of the p101 protein due to low levels of...
Changes in protein expression can alter gene function since: High levels of protein mean that the protein can sustain mutations more readily without any harm to the cell. The cell responds only to high levels of protein. Changes in expression can alter regulatory networks. Low levels of protein mean that the protein can sustain mutations more readily without any harm to the cell. The mutations found in the CF gene that result in cystic fibrosis are recessive because: The CF...
What is the relationship between protein translation and gene expression? Would you expect to always see correlation between these two? Discuss a circumstance within the context of cancer where mRNA and protein expression may not correlate. Why is it important to look at both protein and RNA levels of a series of genes/proteins in a molecular pathway? Discuss this in the context of cancer associated pathways. Give a specific example of a pathway that is independent of gene expression in...
Please briefly explain the Regulation of Gene Expression in Eukaryotes at various levels (Please explain EACH): - Chromatin Structure/ Epigenetics - Transcriptional control - Processing and Stability of mRNA - Translational Control - Posttranslational control of protein function - Eliminating the Protein
Briefly describe the five levels of regulation of eukaryotic gene expression
Two-step model of constitutive unregulated gene expression.
a) Write down the corresponding system of coupled ordinary
differential equations (ODEs) based on mass action kinetics.
Identify and explain which biological/biochemical process the
“source” and “sink” terms in each equation describe.
b) State the parameters for steady-state mRNA and protein
levels.
OM promoter (A) mRNA (M) protein (P) Figure 1. Two-step model of constitutive (unregulated) gene expression. Here the promoter (A) is a constant and represents a gene.
Describe a way in which a membrane bound signal receptor protein could directly regulate gene expression at the level of transcription activation. If there was an intermediate enzyme in this pathway, what effect could that have?
Which of the following is the most appropriate indication of gene expression level? A ONA 6. Protein CRNA DmRNA QUESTION 14 In reality, what is being directly quantified in real-time rt-PCR to estimate the gene expression level? OM Protein levels by amplifying with ribosomes using fluorescently tagged amino acids B. DNA which is amplified with gene-specific primers and measured for fluorescence Reverse transcriptase levels which indicates rate of mRNA transcription O mRNA which is amplified with gene-specific primers and measured...
What do source and sink mean in unregulated gene expression?
OM op promoter (A) mRNA (M) protein (P)
Using Western Blot analysis, you have determined that protein levels of the insulin receptor increase in cultured fibroblast cells after treatment with a new drug. Which of the following hypotheses could explain how this drug could increase protein levels (select all correct answers). A The drug could increase export of the mRNA from the nucleus, thus increasing mRNA levels and protein levels. B The drug could increase expression of the gene, therefore increasing mRNA levels and protein synthesis. C The...