Question

Name some positive strand RNA viruses. How do they replicate? Name some negative strand RNA viruses. How do they replicate and synthesis protein?

Answer 1

A few Positive Strand RNA viruses are as follows:

Okavirus

Alphamesonivirus

Torovirus

Betacoronavirus

How Positive Strand RNA viruses replicate themselves:

Positive stranded RNA serves both as genomic and mRNA for these viruses. Upon infection, the genomic/mRNA is translated, often into a polyprotein encoding for replication machinery. The replication occurs in membranous invaginations of the REG, possibly to avoid dsRNA intermediate detection. Replication of the positive strand presumably leads to dsRNA formation, which in turn will be transcribed into positive single stranded genomic/mRNA. The neo-synthesized RNA may serve either for replication or translation.

A few Negative Strand RNA viruses are as follows:

Deltavirus

Ebola virus,

human respiratory syncytial virus,

measles virus,

mumps virus,

Nipah virus

How Negative Strand RNA viruses replicate themselves and synthesizes proteins:

Negative sense RNA viruses need RNA polymerase to form a positive sense RNA. The positive-sense RNA acts as a viral mRNA, which is translated into proteins for the production of new virion materials. With the newly formed virions, more negative sense RNA molecules are produced.