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Describe the signalling pathways that are active at the 4 cell stage of development in C....

Describe the signalling pathways that are active at the 4 cell stage of development in C. elegans.

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Signalling pathways are the key biological mechanism that transdue extracellular signals to affect transcription factor mediated gene regulations within cells a number of computational methods have been developed to identify the topological structure of a specific signaling pathway using protein-protien interaction data, but they are not design for identify active signalling pathway in an unbaised manner on the other hand, there are statistics methods based on gene sets for pathway data that can prioritize likely active signalling pathway, but they do not make full use of active pathway structure that link receptor, kinases and downstream transcription factor

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