What hypothetical mutation could you make to any mechanism so that when a cell replicates its...
What hypothetical mutation could you make to any mechanism so that when a cell replicates its DNA, the cell will die after? Think of two mutations. This is just 100% hypothetical and you could make up any mutation to any mechanism in replication, such as a beta clamp not working or something along those lines.
Homework Answers
Wow! Great question :)
So we can make n number of mutation to make cell die :)
1. When the replication of DNA start and enzyme helicase opens the DNA, there is a mutation in the helicase enzyme which cause it to open the whole DNA (not the particular segment) which causes high tension in the structure of DNA leading to breaking up of its structure.
2. DNA polymerase enzyme instead of adding new nucleotides bases, start removing bases from the parent strand again leading to destruction in structure of DNA and ultimately cell dies.
3. When DNA replication is getting completed (in the end) when DNA ligase join the fragments, it joins the wrong fragments with each other leading to instability in DNA and mis-match information. Ultimately leading to death of organisim.
You can choose any 2 :) hope it helps, please hit like :)
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What hypothetical mutation could you make to any mechanism so
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know
if any of the mutations affect the stability of the RNA
transcript, thereby leading to higher
turnover and lower overall mRNA levels. What techniques could
you use to test her
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think of at least three methods
you could use)
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QUESTION 13
Which of the following would occur if a mutation caused Kinase 1
to be unable to be phosphorylated? (Select all)
RTK would bind VEGF
RTK would phosphorylate itself
RAS would become active
The phosphorylation cascade would occur
The endothelial cell would divide
0.2 points
QUESTION 14
Imagine that an endothelial cell has a mutation in several of
the enzymes that perform mismatch repair. The endothelial cell
replicates its DNA and then divides into two cells. The resulting...
please match and write with clear handwriting thank
you!
QUESTION 1 All organisms must duplicate their DNA with extraordinary accuracy before each cell division A mixture of proteins accompishes DNA replication. Each of the proteins act independent of one another yet held together in a large multi-enryme complex that moves rapidly along the DNA. Imagine a tiny sewing machine composed of protein parts and powered by nucleosidetriphosphate hydrolases Match the protein subunit or factor of the replication machine to the...
Could you help with any of these ? and provide an explanation
so I'll understand? thank you so much
Circle all that apply 1) A patient has inherited two defective genes for TAP2 (remember the case study from before) Which of the following are true? (circle all that apply): - The patient will have a scarcity of CD4+ T helper cells -MHC class I molecules will not be expressed to any extent on the patient's cells -MHC class II molecules...
Question 2:
a)
You determine that
xpd
is expressed preferentially in muscle. Your colleague wants to
know
if any of the mutations affect the stability of the RNA
transcript, thereby leading to higher
turnover and lower overall mRNA levels. What techniques could
you use to test her
hypothesis? List the pros and cons of each method. (hint: try to
think of at least three methods
you could use)
b) You find that your collegue is correct, and that the xpda...
DNA DNA Replication: ONA Because DNA Is the ge m Tumes and heart e ine in process called DNA curs in the nucleus of s acest FS Parent strand Parent strand Newly replicated DNA Newly replicated DNA- SA0 Daughter DNA molecule Daughter DNA molecule Figure 8.2: Overview of DNA replication and illustration of complementary base pairing. DNA must replicate before cell division so that each new daughter cell receives an exact copy of the parent DNA. 1. Replication begins when...
2. Ok... so, what is the α-synuclein mutant a mouse
model of? (2 points) a) Parkinson’s disease b) Alzheimer’s disease
c) ALS
In your continued work at BigPharma, you are running additional experiments with previously developed, FDA approved drugs to see if they can be used off-label to assist with the treatment of neurodegenerative disorders. Originally, NeuroStop was developed to attenuate brain damage following stroke, and thus might be a good candidate drug for helping slow neurodegeneration. Presented here are data...
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