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Compare the effectiveness of molecular diffusion in a simple organism (unicellular) versus a multi-cellular organism. What...

Compare the effectiveness of molecular diffusion in a simple organism (unicellular) versus a multi-cellular organism. What are the limitations of diffusion and how do multi-cellular organisms overcome these problems?

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Simple organism - Diffusion more effective over only in small distance.
Simple organism have Surface area / volume ratio is large. So, diffusion is of nutrients pass very fast in the membrane.

Multi cellular organisms - Surface area / volume ratio is small. So, the diffusion is very low in the membrane.

The limitation of diffusion - based on size, shape, and function of cells. Diffusion occurs only over small distances so it limits size and shape of the cells.
The multi-cellular organisms overcome these problems by using carrier protein by active process using ATP or against the gradient.

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