Some viral genes rely on frameshifts that alter the stop codon. Find one example and explain...
Some viral genes rely on frameshifts that alter the stop codon. Find one example and explain the details of the mechanism.
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Question
A frameshift is a mutation that alter the reading frame of the genetic codon due to addition or deletion of one or more nucleotide in the codon. Some virus cause the disease that alter the stop codon and therefore result in the formation of new polypeptide sequence that have another stop codon. This new polypeptide cause disease to the host. For example, Epstein-Barr virus, associated with causing human cancer alter the stop codon and lead to the formation of proteins that cause cancer.
Figure: Mechanims of frame shift mutation
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Some viral genes rely on frameshifts that alter the stop codon.
Find one example and explain...
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Find one example of an anti-cancer or anti- viral drug (other types of drugs are also okay) that has at least one chiral center in its structure. Write a brief overview of how this drug used and why it is effective (cite source!). Draw its structure and mark all the stereocenters with a star. Assign each stereocenter as R or S (in case the drug is used as a racemic mixture you can show one of the stereoisomers as...
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