HomeworkLib
Question

The gene APC encodes a protein important for cell-cell adhesion and contact inhibition, the phenomenon in...

The gene APC encodes a protein important for cell-cell adhesion and contact inhibition, the

phenomenon in which cells know when to stop dividing based on interaction with neighboring

cells. A mutation in APC is associated with colon cancer. How is this gene classified?

a. tumor-suppressor

b. passenger mutation

c. gene mutation

d. proto-oncogene

science   biology   
0 0
Add a comment Improve this question Transcribed image text
Next > < Previous
Sort answers by oldest

Homework Answers

Answer #1

In order to develop into cancer, a tumor suppressor gene must exhibit loss of function mutation. In the given case, APC gene is responsible for the cell-cell adhesion and contact inhibition which hinder carcinogenesis. Thus, in order to develop colon cancer, this gene must lose its function. Hence, option A is correct.

0 0
Add a comment
Know the answer?
Add Answer to:
The gene APC encodes a protein important for cell-cell adhesion and contact inhibition, the phenomenon in...
Your Answer:

Post as a guest

Your Name:

What's your source?

Earn Coins

Coins can be redeemed for fabulous gifts.

Log In

Sign Up

Not the answer you're looking for? Ask your own homework help question. Our experts will answer your question WITHIN MINUTES for Free.
Similar Homework Help Questions

  • 1.The KRAS gene encodes the KRAS protein which functions to promote cell growth and division. A...

    1.The KRAS gene encodes the KRAS protein which functions to promote cell growth and division. A single base-pair deletion occurs in exon 4 of the KRAS gene that results in an early stop codon. This mutation results in an unregulated KRAS protein that always sends growth signals. What is a correct classification of the normal (wildtype) KRAS gene? A) A tumor suppressor gene B) An oncogene C) A tumor activating gene D) A DNA repair gene E) A proto-oncogene 2....

  • Cancer and Gene Regulation Why is a cell cycle control system needed for cell division? What...

    Cancer and Gene Regulation Why is a cell cycle control system needed for cell division? What happens when cells do NOT respond to the cell cycle control system and divide excessively? Tumor Proto-oncogeno (for protein that stimulates coll division) 6 Y DNA Benign Tumor= Mutation withln a control region of DNA Malignant Tumor Mutated promoter Metastasis Normal growth-stimulating protein in excess Oncogene Tumor-Suppressor Genes Proto-oncogene utled tara gese Samor-auppresr gane Many proto-oncogenes code for growth factors /Deletive nonimenig Normel grewt...

  • Please help with answers to these questions answer the ones that are straightforward like this one...

    Please help with answers to these questions answer the ones that are straightforward like this one Question 24 5 pts 1. Beta-catenin is classified as a proto-oncogene and APC is classified as a tumor suppressor gene. Both are important parts of the Wnt signaling pathway. Describe the relationship between beta-catenin and APC. Explain in detail why they are classified as a proto-oncogene or tumor suppressor gene. 2. Suppose you're working in a cancer research lab and discover a small molecule...

  • IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS OUTCOME 5. a), Why are Proto-Oncogenes important for...

    IN CONTEXT OF GENE EXPRESSION AND PROTEIN SYNTHESIS OUTCOME 5. a), Why are Proto-Oncogenes important for the cell cycle control and what is their implication in a progression of tumors and cancers? Provide examples of TWO proto-oncogenes and a type of a cancer each is associated with. (6 pts) b) Now consider the diagram below. Under each of three scenarios, explain a likely cellular consequence relative to gene expression and protein synthesis outcome, assuming each could lead to a development...

  • There are two main types of cells in the human brain, neurons (nerve cells) and glial...

    There are two main types of cells in the human brain, neurons (nerve cells) and glial cells (supporting cells). Once neurons fully mature, these nerve cells no longer divide. Glial cells, however, continue to divide over a person’s entire lifetime. GDNF (glial cell line-derived neurotrophic factor) is a small protein that stimulates growth in glial cells. What kind of signal molecule is this protein? How does GDNF likely promote cell division? After the glial cell receives GDNF, what will happen...

  • You are an oncologist (cancer doctor) who specializes in pioneering new advances in cancer therapies. You...

    You are an oncologist (cancer doctor) who specializes in pioneering new advances in cancer therapies. You have been given an exciting new gene therapy treatment that aims at increasing the levels of the p53 protein in tumor cells that have lost all functional p53. You have a cancer patient who is going to be one of the first people ever to receive this treatment since their tumor cells have mutated versions of p53. But they have many questions about the...

  • Question 25 3 pts Given the following DNA template, the sequence of the protein made is:...

    Question 25 3 pts Given the following DNA template, the sequence of the protein made is: 5'-AGC TCG AAT TCG CTT CAT GCT AGC TAG------(+1)--------(-10) ----------(-35) Leu-Ala-Cys-Met-Lys-Arg.lle-Arg-Ala Asp-Arg-Ser-Tyr-Phe-Ala-Stop Met-Ala-Ser-Stop Met-Lys-Arg-lle Arg-Ala Ser-Ser-Asp-Ser-Leu-His-Alo Ser-Stop 3 pts Question 30 In a cancer genomes database, you find multiple mutations in the BMV gene in several types of cancers. The majority of these cancer-associated mutations are heterozygous (having also one wild type allele), and expression of these mutant versions of BMV in normal cells...

  • The dopamine transporter gene encodes a protein required to re-uptake dopamine into the pre-synaptic neuron from...

    The dopamine transporter gene encodes a protein required to re-uptake dopamine into the pre-synaptic neuron from the synapse. How might a variant allele of the dopamine transporter gene, which results in a transporter protein with increased function , be involved in predisposing an individual to addictive behavior? A) The dopamine transporter variant allele would produce more dopamine in response to addictive behavior B) The dopamine transporter variant allele would produce less dopamine in response to addictive behavior C) The dopamine...

  • Part IV—The APC Protein “Sam, I’m really worried about seeing my test results today,” Jane said...

    Part IV—The APC Protein “Sam, I’m really worried about seeing my test results today,” Jane said as they headed in for another visit with their genetic counselor. “After Ms. Meeker explained your results to us, I’ve been dreading hearing whether or not I have the mutation too.” Sam nodded, saying, “I can understand how you feel. I’m glad I can be here at the appointment to support you. Whatever happens, you know your family is here for you.” Ms. Meeker...

  • QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin,...

    QUESTION 7 If you inject a G1 cell that contains 36 chromosomes with a G2/M cyclin, what would happen? (hint - look at slide with cell fusion experiments) The G1 cell would complete mitosis with daughter cells that have 18 chromosomes each The G1 cell would enter mitosis but arrest at the spindle checkpoint because the chromosomes were not properly replicated The G1 cell would complete mitosis with daughter cells that have 36 chromosomes each The G1 cell would go...

ADVERTISEMENT
Free Homework Help App
Download From Google Play
Scan Your Homework
to Get Instant Free Answers
Need Online Homework Help?
Ask a Question
Get Answers For Free
Most questions answered within 3 hours.
ADVERTISEMENT
ADVERTISEMENT